Tag: Time-Release

An Albuquerque-based radiation oncologist serving at the New Mexico Cancer Center, Mary Kara Bucci, MD was named one of America’s Top Oncologists in 2009, 2011, and 2012. Having written numerous peer-reviewed articles in medical journals, Dr. Mary Kara Bucci co-authored an article on dosing in intensity-modulated radiotherapy (IMRT) plans, which was published in the International Journal of Radiation Oncology, Biology, Physics.

Titled Method to Account for Dose Fractionation in Analysis of IMRT Plans: Modified Equivalent Uniform Dose (mEUD), the study aimed to improve radiotherapy outcomes by adjusting recommended doses for patients who receive time-release radiation therapy. Specifically, the study sought to determine effective dosing ranges by developing what oncologists call a modified equivalent uniform dose (mEUD), which takes into account the generalized equivalent uniform dose (gEUD) as well as the biologically effective dose.

The study analyzed 41 patients with nasopharyngeal cancer who received IMRT treatment plans. Researchers concluded that combining the gEUD with the biologically effective dose to achieve a modified dosing system offers the advantages of the current generalized dosing system, while also accounting for the effects of time-release radiotherapy.